Filter Results

  • Filter by Pay
  • Filter by Job Type
  • Filter by Working Pattern
  • Filter by Distance From
  • Filter by Industry
  • Job type

    Permanent
  • Location

    Oxford
  • Working Pattern

    Full-time
  • Specialism

    Scientific And Engineering
  • Industry

    Scientific and R&D
  • Pay

    £35,000 - £45,000

Research Associate - TCR Engineering

Your new company

Our client is an early-stage biotech startup fusing artificial intelligence (AI) and advanced high-throughput TCR screening techniques to revolutionise the treatment of solid cancers. Their pioneering AI platform is poised to design high-affinity and specific T-cell-receptor (TCR) based therapies.


Your new role

As a Research Associate, your drive and expertise will spearhead the refinement of our TCR engineering processes. Responsibilities will include:

  • Collaboratively design and characterise TCRs for our entrusted pipeline and new disease targets.
  • Conduct a suite of protein science operations, including expression, purification, and biophysical analysis.
  • Tackle molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
  • Manage tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
  • Join forces with founders, R&D, academia, and industrial stakeholders to fulfil ambitious R&D objectives.
  • Draft, revise, and oversee our repertoire of lab protocols.
  • Offer essential lab support and uphold facility upkeep.


What you'll need to succeed

  • A PhD in Immunology, Cell Biology, Biochemistry, or an alike field, paired with at least 1-2 years of pertinent lab savvy is required.
  • Knowledge of basic molecular biology protocols, with an emphasis on cloning and PCR is preferred.
  • A background in protein expression, purification and biophysical characterisation is preferred.
  • Experience in bioorthogonal chemistry and bioconjugation is preferred.
  • Experience in lipid nanoparticle formulation is preferred.
  • Experience cell and immunological assays (flow cytometry, ELISA etc.) is desired.
  • Experience NGS analysis pipeline (specifically data analysis using software such as R) is desired.
  • SOP documentation experience is desired.
  • The highest standards in lab precision, record maintenance, and documentation.
  • Excellent written and oral communication skills.


What you'll get in return

  • Market-competitive salary
  • A generous leave policy: 25 days holiday, public holidays, plus a day off for your birthday!
  • Access to our fully-equipped private lab within the BioEscalator complex.
  • Flexibility to telecommute as project demands allow.
  • A supportive, cross-disciplinary team fostering a synergistic workplace.


What you need to do now

If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.

If this job isn't quite right for you, but you are looking for a new position, please contact us for a confidential discussion about your career.

Get job alerts for this search

Be the first to hear about jobs which match your search criteria