Job type
PermanentLocation
OxfordWorking Pattern
Full-timeSpecialism
Scientific And EngineeringIndustry
Scientific and R&DPay
£35,000 - £45,000
Research Associate - TCR Engineering
Your new company
Our client is an early-stage biotech startup fusing artificial intelligence (AI) and advanced high-throughput TCR screening techniques to revolutionise the treatment of solid cancers. Their pioneering AI platform is poised to design high-affinity and specific T-cell-receptor (TCR) based therapies.
Your new role
As a Research Associate, your drive and expertise will spearhead the refinement of our TCR engineering processes. Responsibilities will include:
- Collaboratively design and characterise TCRs for our entrusted pipeline and new disease targets.
- Conduct a suite of protein science operations, including expression, purification, and biophysical analysis.
- Tackle molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
- Manage tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
- Join forces with founders, R&D, academia, and industrial stakeholders to fulfil ambitious R&D objectives.
- Draft, revise, and oversee our repertoire of lab protocols.
- Offer essential lab support and uphold facility upkeep.
What you'll need to succeed
- A PhD in Immunology, Cell Biology, Biochemistry, or an alike field, paired with at least 1-2 years of pertinent lab savvy is required.
- Knowledge of basic molecular biology protocols, with an emphasis on cloning and PCR is preferred.
- A background in protein expression, purification and biophysical characterisation is preferred.
- Experience in bioorthogonal chemistry and bioconjugation is preferred.
- Experience in lipid nanoparticle formulation is preferred.
- Experience cell and immunological assays (flow cytometry, ELISA etc.) is desired.
- Experience NGS analysis pipeline (specifically data analysis using software such as R) is desired.
- SOP documentation experience is desired.
- The highest standards in lab precision, record maintenance, and documentation.
- Excellent written and oral communication skills.
What you'll get in return
- Market-competitive salary
- A generous leave policy: 25 days holiday, public holidays, plus a day off for your birthday!
- Access to our fully-equipped private lab within the BioEscalator complex.
- Flexibility to telecommute as project demands allow.
- A supportive, cross-disciplinary team fostering a synergistic workplace.
What you need to do now
If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.
If this job isn't quite right for you, but you are looking for a new position, please contact us for a confidential discussion about your career.