Director - CAR T-Cell Development - London Biotech

CAR-T, T-cell, oncology, biology, science, scientist, research, drug, protein, discovery, preclinical, cell,

My client is an emerging London based biotech that are working on the latest generation of T-cell based therapeutics to combat a portfolio of hard to tackle and rare diseases. They are looking for an accomplished scientist to help lead a programme developing CAR T-cell biotherapeutics.

The Role

  • Lead, recruit and grow a team of research scientist dedicated to developing novel CAR T-cells against preclinical targets
  • Provide scientific strategy and direction for CAR T development
  • Guide the team on choice and design different gene editing options
  • Collaborate in the development of assays to evaluate the related gene modifications
  • Coordinate efforts among internal groups and external academic collaborators

Required Skills

  • Extensive experience in designing and developing cell-based immunotherapies with CAR T cells (oncology and/or autoimmune diseases)
  • Strong knowledge of T cell biology and cellular signalling
  • Hands-on experience in molecular and cell biology, including experience with T cell transduction and expansion
  • Strong expertise in immunological assays, such as cell based assays for T cell signalling, cytotoxicity, cytokine secretion, proliferation, suppression and exhaustion
  • Demonstrated ability developing and executing research plans

Preferred Skills

  • Experience with gene editing on transgenic TCR T cells and gene editing systems such as CRISPR/Cas
  • Knowledge and experience on allo-recognition and autoimmune biology
  • Insights into immunological tolerance and T cell homeostasis in inflammatory microenvironments

The Benefits

  • Rapidly expanding Biotech working on cutting edge therapeutics
  • Complex and Exciting Projects
  • Great Progression Opportunity
  • Highly Competitive Salary plus an excellent Benefits Package
  • London based

If you think you match the skills listed above and are looking for a new challenge in the Biotech industry, then please apply with your CV or call William Ashbrook on 020 3465 0043 for a completely confidential chat about your situation.


Job type:
Scientific and R&D
Research And Development
Apply Now

Talk to a consultant

Talk to William Ashbrook, the specialist consultant managing this position, located in London City

4th Floor, 107 Cheapside

Telephone: 020 3465 0043

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